117235-10-6
117235-10-6 structure
- Name: 3-Mercaptopropionic acid NHS ester
- Chemical Name: (2,5-dioxopyrrolidin-1-yl) 3-sulfanylpropanoate
- CAS Number: 117235-10-6
- Molecular Formula: C7H9NO4S
- Molecular Weight: 203.21600
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2017-08-17 04:04:03
- Modify Date: 2024-02-01 11:46:00
-
3-Mercaptopropanyl-N-hydroxysuccinimide ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | (2,5-dioxopyrrolidin-1-yl) 3-sulfanylpropanoate |
|---|---|
| Synonyms |
3-Mercapropropanoyl-N-hydroxysuccinimide ester
1-(3-mercapto-1-oxopropoxy)-2,5-pyrrolidinedione |
| Description | 3-Mercaptopropanyl-N-hydroxysuccinimide ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1] |
| References |
| Density | 1.40±0.1 g/cm3 |
|---|---|
| Boiling Point | 318.4±44.0 °C |
| Molecular Formula | C7H9NO4S |
| Molecular Weight | 203.21600 |
| Exact Mass | 203.02500 |
| PSA | 102.48000 |
| Hazard Codes | Xi |
|---|