Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Ginkgolide J
Price: ￥1278.0/20mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Ginkgolide J
Price: $280.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

107438-79-9

107438-79-9 structure

107438-79-9 structure

Name: Ginkgolide J
Chemical Name: Ginkgolide J
CAS Number: 107438-79-9
Molecular Formula: C₂₀H₂₄O₁₀
Molecular Weight: 424.399
Catalog: Biochemical Plant extracts
Create Date: 2018-03-06 08:00:00
Modify Date: 2024-01-02 12:05:11
Ginkgolide J is a main constituent of the non-flavone fraction of Ginkgo biloba with an IC50 range of 12-54 µM, has neuroprotective and anti neuronal apoptotic ability[1][2].

Name	Ginkgolide J
Synonyms	6H-9,4a-(Epoxymethano)-3aH,9H-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-2,6,13(1H)-trione, 11-(1,1-dimethylethyl)hexahydro-1,4b,10-trihydroxy-5-methyl-, (1R,3aR,4aR,4bR,5S,7aS,8aS,9S,10R,11S,11aS)- (1R,3R,6R,7S,8S,9R,10S,11S,13S,16S,17R)-6,9,17-Trihydroxy-16-methyl-8-(2-methyl-2-propanyl)-2,4,14,19-tetraoxahexacyclo[8.7.2.0.0.0.0]nonadecane-5,15,18-trione GinkgolideJ (1R,3R,6R,7S,8S,9R,10S,11S,13S,16S,17R)-8-tert-Butyl-6,9,17-trihydroxy-16-methyl-2,4,14,19-tetraoxahexacyclo[8.7.2.0.0.0.0]nonadecane-5,15,18-trione Ginkgolid J 7beta-hydroxyginkgolide a

Description	Ginkgolide J is a main constituent of the non-flavone fraction of Ginkgo biloba with an IC50 range of 12-54 µM, has neuroprotective and anti neuronal apoptotic ability[1][2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis
In Vivo	Ginkgolide J (100 μM) treatment reduces the apoptotic damage induced by serum deprivation (24h) or treatment with Staurosporine (200 nM, 24h) in cultured chick embryonic neurons[1].
References	[1]. Ahlemeyer B, et al. Pharmacological studies supporting the therapeutic use of Ginkgo biloba extract for Alzheimer's disease. Pharmacopsychiatry. 2003 Jun; 36 Suppl 1:S8-14. [2]. Sylvia Pietri, et al. Synthesis and Biological Studies of a New Ginkgolide C Derivative: Evidence That the Cardioprotective Effect of Ginkgolides Is Unrelated to PAF Inhibition. DRUG DEVELOPMENT RESEARCH. 2001.54:191-201.

Density	1.6±0.1 g/cm3
Boiling Point	760.4±60.0 °C at 760 mmHg
Melting Point	41-42 °C
Molecular Formula	C₂₀H₂₄O₁₀
Molecular Weight	424.399
Flash Point	273.6±26.4 °C
Exact Mass	424.136932
PSA	148.82000
LogP	-0.68
Vapour Pressure	0.0±5.8 mmHg at 25°C
Index of Refraction	1.651

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
RIDADR	NONH for all modes of transport
WGK Germany	3.0