5399-92-8
5399-92-8 structure
- Name: 6-Chloropurine
- Chemical Name: 4-Chloro-1H-Pyrazolo[3,4-d]Pyrimidine
- CAS Number: 5399-92-8
- Molecular Formula: C5H3ClN4
- Molecular Weight: 154.557
- Catalog: Pharmaceutical intermediate Heterocyclic compound Pyrimidine compound Chloropyrimidine
- Create Date: 2018-12-28 12:13:47
- Modify Date: 2024-01-05 14:49:26
| Name | 4-Chloro-1H-Pyrazolo[3,4-d]Pyrimidine |
|---|---|
| Synonyms |
6-Chloropurine
7H-Purine, 6-chloro- 6-Chloro-1H-purine 1H-Pyrazolo[3,4-d]pyrimidine, 4-chloro- MFCD03030404 1H-purine, 6-chloro- 4-Chloro-1H-pyrazolo[3,4-d]pyrimidine |
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Boiling Point | 348.3±22.0 °C at 760 mmHg |
| Melting Point | >350ºC |
| Molecular Formula | C5H3ClN4 |
| Molecular Weight | 154.557 |
| Flash Point | 195.3±7.9 °C |
| Exact Mass | 154.004623 |
| PSA | 54.46000 |
| LogP | 0.05 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.740 |
| Storage condition | Refrigerator |
| Hazard Codes | Xi |
|---|---|
| HS Code | 2933990090 |
|
~81%
5399-92-8 |
| Literature: Sunesis Pharmaceuticals, Inc Patent: US2009/5359 A1, 2009 ; Location in patent: Page/Page column 18 ; US 20090005359 A1 |
|
~70%
5399-92-8 |
| Literature: ELI LILLY AND COMPANY Patent: WO2008/140947 A1, 2008 ; Location in patent: Page/Page column 36-37 ; WO 2008/140947 A1 |
|
~72%
5399-92-8 |
| Literature: Morrill, Christie; Babu, Suresh; Almstead, Neilg.; Moon, Young-Choon Synthesis (Germany), 2013 , vol. 45, # 13 art. no. SS-2013-C0248-OP, p. 1791 - 1806 |
|
~75%
5399-92-8 |
| Literature: Babu, Suresh; Morrill, Christie; Almstead, Neil G.; Moon, Young-Choon Organic Letters, 2013 , vol. 15, # 8 p. 1882 - 1885 |
|
~%
5399-92-8 |
| Literature: Tetrahedron Letters, , vol. 54, # 38 p. 5204 - 5206 |
| Precursor 5 | |
|---|---|
| DownStream 10 | |
![4-chloro-3-iodo-1H-pyrazolo[3,4-d]pyrimidine structure](https://www.chemsrc.com/caspic/248/1082950-96-6.png)
![3-Bromo-4-chloro-1H-pyrazolo[3,4-d]pyrimidine structure](https://www.chemsrc.com/caspic/163/90914-41-3.png)
![TERT-BUTYL4-(1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YL)PIPERAZINE-1-CARBOXYLATE structure](https://www.chemsrc.com/caspic/272/245450-02-6.png)
![4H-Pyrazolo[3,4-d]pyrimidine-4-thione,1,5-dihydro- structure](https://www.chemsrc.com/caspic/420/5334-23-6.png)
![1H-Pyrazolo[3,4-d]pyrimidine, 4-ethoxy- structure](https://www.chemsrc.com/caspic/242/32353-19-8.png)
![4-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine structure](https://www.chemsrc.com/caspic/411/23000-43-3.png)
![4-Chloro-2-methyl-2H-pyrazolo[3,4-d]pyrimidine structure](https://www.chemsrc.com/caspic/067/959430-67-2.png)
![1H-Pyrazolo[3,4-d]pyrimidine,4-chloro-1-(tetrahydro-2H-pyran-2-yl)- structure](https://www.chemsrc.com/caspic/430/91446-15-0.png)
![4-chloro-2-(tetrahydro-pyran-2-yl)-2H-pyrazolo[3,4-d]pyrimidine structure](https://www.chemsrc.com/caspic/227/847448-60-6.png)
![5-ethylsulfanyl-2,4,8,9-tetrazabicyclo[4.3.0]nona-2,4,7,10-tetraene structure](https://www.chemsrc.com/caspic/409/5470-54-2.png)
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |