BioBioPha
China
Product Name: 2-Methoxy-1,4-naphthoquinone
Price: ￥Inquiry/5mg
Purity: 98.0%
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Contact: Xueping-Zheng

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1,4-Naphthalenedione,2-methoxy-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

2348-82-5

2348-82-5 structure

2348-82-5 structure

Name: Lawsone methyl ether
Chemical Name: 2-methoxy-1,4-naphthoquinone
CAS Number: 2348-82-5
Molecular Formula: C₁₁H₈O₃
Molecular Weight: 188.17900
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-06-24 15:33:09
Modify Date: 2024-01-07 18:33:20
Lawsone methyl ether (2-Methoxy-1,4-naphthoquinone), isolated from Impatiens balsamina L. and Swertia calycina, exhibits potent antifungal and antibacterial activities[1].

Name	2-methoxy-1,4-naphthoquinone
Synonyms	2-Methoxy-p-naphthoquinone 1,4-Naphthalenedione,2-methoxy 2-methoxy-1,4-naphthalenequinone 2-methoxynaphthalene-1,4-dione 2-Methoxy-[1,4]naphthoquinone 2-methoxyl-1,4-naphthoquinone 2-Methoxynaphthoquinone 1,4-NAPHTHOQUINONE,2-METHOXY MFCD00019539 2-Methoxy-1,4-naphthalenedione Methoxy-1,4-naphthochinin

Description	Lawsone methyl ether (2-Methoxy-1,4-naphthoquinone), isolated from Impatiens balsamina L. and Swertia calycina, exhibits potent antifungal and antibacterial activities[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	The value of both minimal inhibitory concentration and minimal fungicidal concentration of Lawsone methyl ether (2-Methoxy-1,4-naphthoquinone) against Candida was 1.25 lg⁄ml[1].
References	[1]. Sritrairat N, et al. Antifungal activity of lawsone methyl ether in comparison with chlorhexidine. J Oral Pathol Med. 2011 Jan;40(1):90-6.

Density	1.28g/cm3
Boiling Point	339.8ºC at 760mmHg
Melting Point	184-187ºC(lit.)
Molecular Formula	C₁₁H₈O₃
Molecular Weight	188.17900
Flash Point	152.7ºC
Exact Mass	188.04700
PSA	43.37000
LogP	1.59590
Vapour Pressure	8.98E-05mmHg at 25°C
Index of Refraction	1.589
Storage condition	-20℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QL8960000

CHEMICAL NAME :: 1,4-Naphthoquinone, 2-methoxy-

CAS REGISTRY NUMBER :: 2348-82-5

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C11-H8-O3

MOLECULAR WEIGHT :: 188.19

WISWESSER LINE NOTATION :: L66 BV EVJ CO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 320 mg/kg

TOXIC EFFECTS :: Tumorigenic - active as anti-cancer agent

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 26,570,1983

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - wild bird species

DOSE/DURATION :: 316 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume(issue)/page/year: 12,355,1983

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	36/37/38
Safety Phrases	S26;S36
RIDADR	NONH for all modes of transport
RTECS	QL8960000
HS Code	2914690090

Precursor 10
1010-60-2 93-04-9 57404-85-0 1515-76-0
824-46-4 67-56-1 2065-37-4 70477-38-2
60683-53-6 83-72-7
DownStream 10
104202-35-9 33440-64-1 14422-78-7 26037-61-6
84-79-7 3408-13-7 3144-89-6 17241-45-1
24555-42-8 75112-65-1

HS Code	2914690090
Summary	2914690090 other quinones。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%