- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: 3,3'-Disulfanediyldipropanoic acid
- Price: ￥535.0/500g ￥145.0/100g
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Liu jia
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 3,3'-Dithiodipropionic acid suppliers in China
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: 3,3'-DITHIODIPROPIONIC ACID
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
1119-62-6
1119-62-6 structure
- Name: 3,3'-Disulfanediyldipropanoic acid
- Chemical Name: 3,3′-Dithiodipropionic acid
- CAS Number: 1119-62-6
- Molecular Formula: C6H10O4S2
- Molecular Weight: 210.271
- Catalog: Chemical reagent Organic reagent fatty acid
- Create Date: 2018-05-05 08:00:00
- Modify Date: 2024-01-02 12:41:20
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Dithiodipropionic acid can interact with CPUL1 (HY-151802, a TrxR inhibitor) to form nanoaggregates (CPUL1-DA NAs). CPUL1-DA NAs generates more abundant ROS to induce cell apoptosis than that of free CPUL1, and improves antitumor efficacy against HUH7 cancer cells[1].
| Name | 3,3′-Dithiodipropionic acid |
|---|---|
| Synonyms |
MFCD00002780
3-(2-carboxyethyldisulfanyl)propanoic acid Propanoic acid, 3,3'-dithiobis- 3,3'-Dithiodipropionic acid 3,3'-Disulfanediyldipropanoic acid EINECS 214-284-0 3,3-Dithiodipropionic Acid 3,3‘-Dithiodipropionic acid |
| Description | Dithiodipropionic acid can interact with CPUL1 (HY-151802, a TrxR inhibitor) to form nanoaggregates (CPUL1-DA NAs). CPUL1-DA NAs generates more abundant ROS to induce cell apoptosis than that of free CPUL1, and improves antitumor efficacy against HUH7 cancer cells[1]. |
|---|---|
| Related Catalog | |
| In Vitro | CPUL1-DA NAs (molar ratio was 1:2) inhibits HUH7 hepatoma cell viability with an IC50 value of 4.3 μM, and has weak cytotoxicity against normal L02 cells[1]. CPUL1-DA NAs (2.5-10 μM, 6 h) can be more effectively enriched in HUH7 cells mitochondria and displays faster cellular uptake ability to deliver CPUL1 into cells than that of free CPUL1[1]. CPUL1-DA NAs (2.5-10 μM, 12 h) results in the accumulation of superoxides and mitochondrial membrane damage in HUH7 cells[1]. |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 431.1±30.0 °C at 760 mmHg |
| Melting Point | 155-158 °C(lit.) |
| Molecular Formula | C6H10O4S2 |
| Molecular Weight | 210.271 |
| Flash Point | 214.5±24.6 °C |
| Exact Mass | 210.002045 |
| PSA | 125.20000 |
| LogP | 1.38 |
| Vapour Pressure | 0.0±2.2 mmHg at 25°C |
| Index of Refraction | 1.592 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | C:Corrosive; |
| Risk Phrases | R34 |
| Safety Phrases | S26-S36 |
| RIDADR | 1759 |
| WGK Germany | 3 |
| Packaging Group | III |
| Hazard Class | 8 |
| HS Code | 2930909090 |
| Precursor 10 | |
|---|---|
| DownStream 10 | |
![3-[(2,2-dioxo-1,2λ6-benzoxathiin-4-yl)sulfanyl]propanoic acid structure](https://www.chemsrc.com/caspic/438/95667-99-5.png)
![3-[bis(ethoxycarbonyl)methylthio]propionic acid structure](https://www.chemsrc.com/caspic/394/107106-61-6.png)
![3-[[3-oxo-3-(pyridin-4-ylmethylamino)propyl]disulfanyl]-N-(pyridin-4-ylmethyl)propanamide structure](https://www.chemsrc.com/caspic/070/189573-10-2.png)
![N-benzyl-3-[[3-(benzylamino)-3-oxopropyl]disulfanyl]propanamide structure](https://www.chemsrc.com/caspic/398/2935-91-3.png)
| HS Code | 2930909090 |
|---|---|
| Summary | 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |