3,3'-Disulfanediyldipropanoic acid structure
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Common Name | 3,3'-Disulfanediyldipropanoic acid | ||
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CAS Number | 1119-62-6 | Molecular Weight | 210.271 | |
Density | 1.5±0.1 g/cm3 | Boiling Point | 431.1±30.0 °C at 760 mmHg | |
Molecular Formula | C6H10O4S2 | Melting Point | 155-158 °C(lit.) | |
MSDS | Chinese USA | Flash Point | 214.5±24.6 °C | |
Symbol |
GHS07 |
Signal Word | Warning |
Use of 3,3'-Disulfanediyldipropanoic acidDithiodipropionic acid can interact with CPUL1 (HY-151802, a TrxR inhibitor) to form nanoaggregates (CPUL1-DA NAs). CPUL1-DA NAs generates more abundant ROS to induce cell apoptosis than that of free CPUL1, and improves antitumor efficacy against HUH7 cancer cells[1]. |
Name | 3,3′-Dithiodipropionic acid |
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Synonym | More Synonyms |
Description | Dithiodipropionic acid can interact with CPUL1 (HY-151802, a TrxR inhibitor) to form nanoaggregates (CPUL1-DA NAs). CPUL1-DA NAs generates more abundant ROS to induce cell apoptosis than that of free CPUL1, and improves antitumor efficacy against HUH7 cancer cells[1]. |
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Related Catalog | |
In Vitro | CPUL1-DA NAs (molar ratio was 1:2) inhibits HUH7 hepatoma cell viability with an IC50 value of 4.3 μM, and has weak cytotoxicity against normal L02 cells[1]. CPUL1-DA NAs (2.5-10 μM, 6 h) can be more effectively enriched in HUH7 cells mitochondria and displays faster cellular uptake ability to deliver CPUL1 into cells than that of free CPUL1[1]. CPUL1-DA NAs (2.5-10 μM, 12 h) results in the accumulation of superoxides and mitochondrial membrane damage in HUH7 cells[1]. |
References |
Density | 1.5±0.1 g/cm3 |
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Boiling Point | 431.1±30.0 °C at 760 mmHg |
Melting Point | 155-158 °C(lit.) |
Molecular Formula | C6H10O4S2 |
Molecular Weight | 210.271 |
Flash Point | 214.5±24.6 °C |
Exact Mass | 210.002045 |
PSA | 125.20000 |
LogP | 1.38 |
Vapour Pressure | 0.0±2.2 mmHg at 25°C |
Index of Refraction | 1.592 |
Symbol |
GHS07 |
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Signal Word | Warning |
Hazard Statements | H315-H319-H335 |
Precautionary Statements | P261-P305 + P351 + P338 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
Hazard Codes | C:Corrosive; |
Risk Phrases | R34 |
Safety Phrases | S26-S36 |
RIDADR | 1759 |
WGK Germany | 3 |
Packaging Group | III |
Hazard Class | 8 |
HS Code | 2930909090 |
Precursor 10 | |
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DownStream 10 | |
HS Code | 2930909090 |
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Summary | 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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MFCD00002780 |
3-(2-carboxyethyldisulfanyl)propanoic acid |
Propanoic acid, 3,3'-dithiobis- |
3,3'-Dithiodipropionic acid |
3,3'-Disulfanediyldipropanoic acid |
EINECS 214-284-0 |
3,3-Dithiodipropionic Acid |
3,3‘-Dithiodipropionic acid |