878339-23-2

878339-23-2 structure

Name: L-Phenylalanine-13C9,15N
Chemical Name: Phenylalanine-ul-13C,15N
CAS Number: 878339-23-2
Molecular Formula: ₁₃C₉H₁₁₁₅NO₂
Molecular Weight: 175.11600
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Calcium Channel
Create Date: 2017-01-07 08:12:10
Modify Date: 2024-01-19 14:17:54
L-Phenylalanine-13C9,15N ((S)-2-Amino-3-phenylpropionic acid-13C9,15N) is the 13C- and 15N-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].

Name	Phenylalanine-ul-13C,15N
Synonyms	L-Phenylalanine-13C9,15N

Description	L-Phenylalanine-13C9,15N ((S)-2-Amino-3-phenylpropionic acid-13C9,15N) is the 13C- and 15N-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Metabolic Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H332
Hazard Codes	Xi
RIDADR	NONH for all modes of transport