L-Phenylalanine-13C9,15N

Modify Date: 2024-01-19 14:17:54

L-Phenylalanine-13C9,15N Structure
L-Phenylalanine-13C9,15N structure
Common Name L-Phenylalanine-13C9,15N
CAS Number 878339-23-2 Molecular Weight 175.11600
Density N/A Boiling Point N/A
Molecular Formula 13C9H1115NO2 Melting Point 270-275 °C(dec.)(lit.)
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of L-Phenylalanine-13C9,15N


L-Phenylalanine-13C9,15N ((S)-2-Amino-3-phenylpropionic acid-13C9,15N) is the 13C- and 15N-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].

 Names

Name Phenylalanine-ul-13C,15N
Synonym More Synonyms

 L-Phenylalanine-13C9,15N Biological Activity

Description L-Phenylalanine-13C9,15N ((S)-2-Amino-3-phenylpropionic acid-13C9,15N) is the 13C- and 15N-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

 Chemical & Physical Properties

Melting Point 270-275 °C(dec.)(lit.)
Molecular Formula 13C9H1115NO2
Molecular Weight 175.11600
Exact Mass 175.10600
PSA 63.32000
LogP 1.34130

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H332
Hazard Codes Xi
RIDADR NONH for all modes of transport

 Synonyms

L-Phenylalanine-13C9,15N