- BioBioPha
- China
- Product Name: 6,7-Dihydroxycoumarin
- Price: ￥Inquiry/50mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Xueping-Zheng
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: 6,7-Dihydroxycoumarin
- Price: ￥68.0/20mg ￥348.0/5g ￥118.0/1g
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Esculetin
- Price: $280.0/20mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: Esculetin
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: TIANFU-CHEM - Esculetin
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
305-01-1
305-01-1 structure
- Name: 6,7-Dihydroxycoumarin
- Chemical Name: esculetin
- CAS Number: 305-01-1
- Molecular Formula: C9H6O4
- Molecular Weight: 178.141
- Catalog: API Respiratory medication Asthma
- Create Date: 2018-07-08 19:23:40
- Modify Date: 2024-01-02 17:41:39
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Esculetin is an active ingredient extracted mainly from the bark of Fraxinus rhynchophylla. Esculetin inhibits platelet-derived growth factor (PDGF)-induced airway smooth muscle cells (ASMCs) phenotype switching through inhibition of PI3K/Akt pathway. Esculetin has antioxidant, antiinflammatory, and antitumor activities[1].
| Name | esculetin |
|---|---|
| Synonyms |
Aesculetin
Cryptotanshinone ESCULETOL CICHERINGENIN Cichorigenin Asculetine Esculatin 6,7-Dihydroxycoumarin Esculin aglycon 6,7-Dihydroxy-2H-chromen-2-one esculetin 2H-1-Benzopyran-2-one, 6,7-dihydroxy- 6,7-dihydroxy-2H-1-benzopyran-2-one Coumarin, 6,7-dihydroxy- MFCD00006874 EINECS 206-161-5 |
| Description | Esculetin is an active ingredient extracted mainly from the bark of Fraxinus rhynchophylla. Esculetin inhibits platelet-derived growth factor (PDGF)-induced airway smooth muscle cells (ASMCs) phenotype switching through inhibition of PI3K/Akt pathway. Esculetin has antioxidant, antiinflammatory, and antitumor activities[1]. |
|---|---|
| Related Catalog | |
| Target |
PI3K Akt |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 469.7±45.0 °C at 760 mmHg |
| Melting Point | 271-273 °C(lit.) |
| Molecular Formula | C9H6O4 |
| Molecular Weight | 178.141 |
| Flash Point | 201.5±22.2 °C |
| Exact Mass | 178.026611 |
| PSA | 70.67000 |
| LogP | 0.98 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.689 |
| Storage condition | 2-8°C |
| Water Solubility | slightly soluble |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36-S37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | GN6382500 |
| Packaging Group | I; II; III |
| HS Code | 2932209090 |
| Precursor 9 | |
|---|---|
| DownStream 10 | |
![[1,3]dioxolo[4,5-g]chromen-6-one structure](https://www.chemsrc.com/caspic/030/494-56-4.png)
| HS Code | 2932209090 |
|---|---|
| Summary | 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |