Name | 6,7-Dimethoxycoumarin |
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Synonyms |
MFCD00006871
6,7-Dimethoxy-chromen-2-one Scoparone EINECS 204-369-0 Dimethylesculetin 6,7-dimethoxychromen-2-one 6,7-Dimethoxy-2H-chromen-2-one 2H-1-Benzopyran-2-one, 6,7-dimethoxy- |
Description | Scoparone is isolated from Artemisia capillaris, has anticoagulant, vasorelaxant antioxidant, anti-inflammatory activities[1]. |
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Related Catalog | |
In Vitro | Scoparone (0-0.4 nM; 24-48 hours) produces the most inhibition on PSC proliferation at 0.4 nM[1]. |
In Vivo | Scoparone (oral administration; 30 mg/kg, 60 mg/kg; 4 weeks) greatly ameliorates the pancreatic weight loss induced by DBTC in pancreatitis rats[1]. Animal Model: Chronic Pancreatitis (CP) Rat Models[1] Dosage: 30 mg/kg, 60 mg/kg Administration: Oral administration; 30 mg/kg, 60 mg/kg; 4 weeks Result: Protected against pancreatic damage |
References |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 369.2±42.0 °C at 760 mmHg |
Melting Point | 145°C |
Molecular Formula | C11H10O4 |
Molecular Weight | 206.195 |
Flash Point | 166.8±27.9 °C |
Exact Mass | 206.057907 |
PSA | 48.67000 |
LogP | 1.60 |
Vapour Pressure | 0.0±0.8 mmHg at 25°C |
Index of Refraction | 1.557 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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Symbol |
GHS06 |
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Signal Word | Danger |
Hazard Statements | H301-H319 |
Precautionary Statements | P301 + P310-P305 + P351 + P338 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
Hazard Codes | Xn: Harmful; |
Risk Phrases | R23/24/25 |
Safety Phrases | S27/28-S36/37/39-S45-S26 |
RIDADR | 2811 |
RTECS | GN6550000 |
Packaging Group | III |
Hazard Class | 6.1(b) |
HS Code | 2932209090 |
Precursor 9 | |
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DownStream 5 | |
HS Code | 2932209090 |
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Summary | 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |