5498-83-9
5498-83-9 structure
- Name: m-PEG5-NH2
- Chemical Name: 3-(2-chloroquinolin-3-yl)-1-phenylprop-2-en-1-one
- CAS Number: 5498-83-9
- Molecular Formula: C11H25NO5
- Molecular Weight: 251.32000
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2019-01-12 10:39:01
- Modify Date: 2024-01-05 18:27:59
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m-PEG5-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 3-(2-chloroquinolin-3-yl)-1-phenylprop-2-en-1-one |
|---|---|
| Synonyms | 2,5,8,11,14-Pentaoxahexadecan-16-amine |
| Description | m-PEG5-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.023g/cm3 |
|---|---|
| Boiling Point | 324.5ºC at 760 mmHg |
| Molecular Formula | C11H25NO5 |
| Molecular Weight | 251.32000 |
| Flash Point | 143.5ºC |
| Exact Mass | 251.17300 |
| PSA | 72.17000 |
| LogP | 0.35820 |
| Index of Refraction | 1.444 |
| Storage condition | 2-8°C |
| HS Code | 2921199090 |
|---|
|
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5498-83-9 |
| Literature: Journal of the American Chemical Society, , vol. 116, # 12 p. 5057 - 5062 |
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5498-83-9 |
| Literature: Journal of the American Chemical Society, , vol. 116, # 12 p. 5057 - 5062 |
| Precursor 2 | |
|---|---|
| DownStream 0 | |
| HS Code | 2921199090 |
|---|---|
| Summary | 2921199090 other acyclic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |