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  • Product Name: Tigogenin
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77-60-1

77-60-1 structure
77-60-1 structure
  • Name: Tigogenin
  • Chemical Name: (25R)-5.α.-Spirostan-3.β.-ol
  • CAS Number: 77-60-1
  • Molecular Formula: C27H44O3
  • Molecular Weight: 416.637
  • Catalog: Natural product Steroidal compound
  • Create Date: 2018-09-30 20:25:24
  • Modify Date: 2024-01-02 16:44:33
  • Tigogenin, one of steroidal sapogenins, is widely used for synthesizing steroid drugs. Tigogenin inhibits adipocytic differentiation and induces osteoblastic differentiation in mouse bone marrow stromal cells[1].

Name (25R)-5.α.-Spirostan-3.β.-ol
Synonyms 5α-Spirostan-3β-ol, (25R)-
TIGOGENIN
Tsosarsasaprgein
(3β,5α,25R)-Spirostan-3-ol
MFCD00067287
Ticogenin
(25R)-5a-Spirostan-3b-ol
(25R)-5α-Spirostan-3β-ol
Sisalagenin
Trigonegenin B
EINECS 201-041-9
Spirostan-3-ol, (3β,5α,25R)-
Description Tigogenin, one of steroidal sapogenins, is widely used for synthesizing steroid drugs. Tigogenin inhibits adipocytic differentiation and induces osteoblastic differentiation in mouse bone marrow stromal cells[1].
Related Catalog
References

[1]. Zhou H, et al. Tigogenin inhibits adipocytic differentiation and induces osteoblastic differentiation in mouse bone marrow stromal cells. Mol Cell Endocrinol. 2007 May 30;270(1-2):17-22.

Density 1.1±0.1 g/cm3
Boiling Point 516.6±20.0 °C at 760 mmHg
Melting Point 202-204ºC
Molecular Formula C27H44O3
Molecular Weight 416.637
Flash Point 266.2±21.8 °C
Exact Mass 416.329041
PSA 38.69000
LogP 6.21
Vapour Pressure 0.0±3.0 mmHg at 25°C
Index of Refraction 1.552

CHEMICAL IDENTIFICATION

RTECS NUMBER :
WH1443500
CHEMICAL NAME :
5-alpha-Spirostan-3-beta-ol, (25R)-
CAS REGISTRY NUMBER :
77-60-1
LAST UPDATED :
199709
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C27-H44-O3
MOLECULAR WEIGHT :
416.71

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
10 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
29QKAZ "Toxins of Animal and Plant Origin, Proceedings International Symposium, 2nd, 1970," de Vries, A., and E. Kochva, eds., 3 vols., New York, Gordon and Breach Science Pub., 1971-73 Volume(issue)/page/year: 2,597,1972
Hazard Codes Xi
RTECS WH1443500
Hazard Class 2.3
HS Code 2932999099
HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%