1681056-62-1
1681056-62-1 structure
- Name: PG 34
- Chemical Name: PG 34
- CAS Number: 1681056-62-1
- Molecular Formula: C28H25N3O5S2
- Molecular Weight: 547.65
- Catalog: Research Areas Others
- Create Date: 2022-10-12 20:09:08
- Modify Date: 2024-01-18 10:20:16
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PG 34 is a weak O-GlcNAc transferase (OGT) inhibitor (IC50=68 μM), and a close structural analog of OSMI-1 (HY-119738)[1].
| Name | PG 34 |
|---|
| Description | PG 34 is a weak O-GlcNAc transferase (OGT) inhibitor (IC50=68 μM), and a close structural analog of OSMI-1 (HY-119738)[1]. |
|---|---|
| Related Catalog | |
| In Vitro | PG34 (0.5-50 µM; 24 h) shows no detectable inhibition of OGT in CHO cells, displays no effect on apoptotic signaling, and shows a moderate effect on cell viability only at the highest concentration[1]. Cell Viability Assay[1] Cell Line: CHO cells Concentration: 0.5-50 µM Incubation Time: 24 hours Result: Inhibited cell growth moderately at 50 µM. Western Blot Analysis[1] Cell Line: CHO cells Concentration: 10, 25, and 50 µM Incubation Time: 24 hours Result: Showed no reduction in global O-GlcNAcylation in cells. |
| References |
| Molecular Formula | C28H25N3O5S2 |
|---|---|
| Molecular Weight | 547.65 |