Name | BOLD-100 |
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Description | BOLD-100 is a ruthenium-based anticancer agent. BOLD-100 also is an inhibitor of stress-induced GRP78 upregulation, disrupting endoplasmic reticulum (ER) homeostasis and inducing ER stress and unfolded protein response (UPR). BOLD-100 interferes with the complex interplay between ER-stress response, lysosome dynamics, and autophagy execution[1]. |
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Related Catalog | |
Target |
GRP78, Autophagy[1] |
References |
Molecular Formula | C14H12Cl4N4Ru |
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Molecular Weight | 479.15 |