1346597-27-0

1346597-27-0 structure

Name: Miglitol-d4 hydrochloride
Chemical Name: Miglitol-d4 hydrochloride
CAS Number: 1346597-27-0
Molecular Formula: C₈H₁₄D₄ClNO₅
Molecular Weight: 247.71
Catalog: Research Areas Metabolic Disease
Create Date: 2021-10-11 21:01:15
Modify Date: 2024-01-10 18:06:38
Miglitol-d4 (BAY1099-d4) hydrochloride is the deuterium labeled Miglitol. Miglitol is an oral anti-diabetic drug that acts by inhibiting the ability of the patient to breakdown complex carbohydrates into glucose[1][2].

Name	Miglitol-d4 hydrochloride

Description	Miglitol-d4 (BAY1099-d4) hydrochloride is the deuterium labeled Miglitol. Miglitol is an oral anti-diabetic drug that acts by inhibiting the ability of the patient to breakdown complex carbohydrates into glucose[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Fukaya, N., et al., The alpha-glucosidase inhibitor miglitol delays the development of diabetes and dysfunctional insulin secretion in pancreatic beta-cells in OLETF rats. Eur J Pharmacol, 2009. 624(1-3): p. 51-7. [3]. Hirata, A., et al., Effect of miglitol, an alpha-glucosidase inhibitor, on atherogenic outcomes in balloon-injured diabetic rats. Horm Metab Res, 2009. 41(3): p. 213-20.

Molecular Formula	C₈H₁₄D₄ClNO₅
Molecular Weight	247.71