Miglitol-d4 hydrochloride

Modify Date: 2024-01-10 18:06:38

Miglitol-d4 hydrochloride Structure
Miglitol-d4 hydrochloride structure
Common Name Miglitol-d4 hydrochloride
CAS Number 1346597-27-0 Molecular Weight 247.71
Density N/A Boiling Point N/A
Molecular Formula C8H14D4ClNO5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Miglitol-d4 hydrochloride


Miglitol-d4 (BAY1099-d4) hydrochloride is the deuterium labeled Miglitol. Miglitol is an oral anti-diabetic drug that acts by inhibiting the ability of the patient to breakdown complex carbohydrates into glucose[1][2].

 Names

Name Miglitol-d4 hydrochloride

 Miglitol-d4 hydrochloride Biological Activity

Description Miglitol-d4 (BAY1099-d4) hydrochloride is the deuterium labeled Miglitol. Miglitol is an oral anti-diabetic drug that acts by inhibiting the ability of the patient to breakdown complex carbohydrates into glucose[1][2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Fukaya, N., et al., The alpha-glucosidase inhibitor miglitol delays the development of diabetes and dysfunctional insulin secretion in pancreatic beta-cells in OLETF rats. Eur J Pharmacol, 2009. 624(1-3): p. 51-7.

[3]. Hirata, A., et al., Effect of miglitol, an alpha-glucosidase inhibitor, on atherogenic outcomes in balloon-injured diabetic rats. Horm Metab Res, 2009. 41(3): p. 213-20.

 Chemical & Physical Properties

Molecular Formula C8H14D4ClNO5
Molecular Weight 247.71