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Related CAS#:

101418-00-2

101418-00-2 structure
101418-00-2 structure
  • Name: Policresulen
  • Chemical Name: 2-hydroxy-3,5-bis[(4-hydroxy-2-methyl-5-sulfophenyl)methyl]-4-methylbenzenesulfonic acid
  • CAS Number: 101418-00-2
  • Molecular Formula: (C7H8O4S.CH2O)x
  • Molecular Weight: 218.22700
  • Catalog: API Synthetic anti-infective drugs Disinfectant antiseptic
  • Create Date: 2018-04-10 08:00:00
  • Modify Date: 2024-01-02 16:41:28
  • Policresulen is a potent inhibitor of DENV2 NS2B/NS3 protease (IC50 of 0.48 μg/mL). Policresulen inhibits DENV2 replication in BHK-21 cells with IC50 of 4.99 μg/mL. Policresulen acts as a competitive inhibitor of the protease, and slightly affects the protease stability[1].

Name 2-hydroxy-3,5-bis[(4-hydroxy-2-methyl-5-sulfophenyl)methyl]-4-methylbenzenesulfonic acid
Synonyms Policresuleno
FC1272
Policresulen
MFCD00869035
Policresulenum
Policresulene
Description Policresulen is a potent inhibitor of DENV2 NS2B/NS3 protease (IC50 of 0.48 μg/mL). Policresulen inhibits DENV2 replication in BHK-21 cells with IC50 of 4.99 μg/mL. Policresulen acts as a competitive inhibitor of the protease, and slightly affects the protease stability[1].
Related Catalog
References

[1]. Wu DW, et al. Policresulen, a novel NS2B/NS3 protease inhibitor, effectively inhibits the replication of DENV2 virus in BHK-21 cells. Acta Pharmacol Sin. 2015;36(9):1126-1136.

Density 1.631 g/cm3
Molecular Formula (C7H8O4S.CH2O)x
Molecular Weight 218.22700
Exact Mass 218.02500
PSA 100.05000
LogP 2.47910
Hazard Codes Xi
HS Code 2908999090
HS Code 2908999090
Summary 2908999090 halogenated, sulphonated, nitrated or nitrosated derivatives of phenols or phenol-alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%