Policresulen

Modify Date: 2024-01-02 16:41:28

Policresulen Structure
Policresulen structure
Common Name Policresulen
CAS Number 101418-00-2 Molecular Weight 218.22700
Density 1.631 g/cm3 Boiling Point N/A
Molecular Formula (C7H8O4S.CH2O)x Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Policresulen


Policresulen is a potent inhibitor of DENV2 NS2B/NS3 protease (IC50 of 0.48 μg/mL). Policresulen inhibits DENV2 replication in BHK-21 cells with IC50 of 4.99 μg/mL. Policresulen acts as a competitive inhibitor of the protease, and slightly affects the protease stability[1].

 Names

Name 2-hydroxy-3,5-bis[(4-hydroxy-2-methyl-5-sulfophenyl)methyl]-4-methylbenzenesulfonic acid
Synonym More Synonyms

 Policresulen Biological Activity

Description Policresulen is a potent inhibitor of DENV2 NS2B/NS3 protease (IC50 of 0.48 μg/mL). Policresulen inhibits DENV2 replication in BHK-21 cells with IC50 of 4.99 μg/mL. Policresulen acts as a competitive inhibitor of the protease, and slightly affects the protease stability[1].
Related Catalog
References

[1]. Wu DW, et al. Policresulen, a novel NS2B/NS3 protease inhibitor, effectively inhibits the replication of DENV2 virus in BHK-21 cells. Acta Pharmacol Sin. 2015;36(9):1126-1136.

 Chemical & Physical Properties

Density 1.631 g/cm3
Molecular Formula (C7H8O4S.CH2O)x
Molecular Weight 218.22700
Exact Mass 218.02500
PSA 100.05000
LogP 2.47910

 Safety Information

Hazard Codes Xi
HS Code 2908999090

 Customs

HS Code 2908999090
Summary 2908999090 halogenated, sulphonated, nitrated or nitrosated derivatives of phenols or phenol-alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

 Synonyms

Policresuleno
FC1272
Policresulen
MFCD00869035
Policresulenum
Policresulene
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