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1539080-27-7

1539080-27-7 structure
1539080-27-7 structure
  • Name: N-Ethylpropionamide-PEG1-Br
  • Chemical Name: N-Ethylpropionamide-PEG1-Br
  • CAS Number: 1539080-27-7
  • Molecular Formula: C7H14BrNO2
  • Molecular Weight: 224.10
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-06-30 22:22:51
  • Modify Date: 2024-01-08 16:09:39
  • N-Ethylpropionamide-PEG1-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name N-Ethylpropionamide-PEG1-Br
Description N-Ethylpropionamide-PEG1-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C7H14BrNO2
Molecular Weight 224.10