N-Ethylpropionamide-PEG1-Br

Modify Date: 2024-01-08 16:09:39

N-Ethylpropionamide-PEG1-Br Structure
N-Ethylpropionamide-PEG1-Br structure
Common Name N-Ethylpropionamide-PEG1-Br
CAS Number 1539080-27-7 Molecular Weight 224.10
Density N/A Boiling Point N/A
Molecular Formula C7H14BrNO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-Ethylpropionamide-PEG1-Br


N-Ethylpropionamide-PEG1-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-Ethylpropionamide-PEG1-Br

 N-Ethylpropionamide-PEG1-Br Biological Activity

Description N-Ethylpropionamide-PEG1-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C7H14BrNO2
Molecular Weight 224.10