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1263166-91-1

1263166-91-1 structure
1263166-91-1 structure
  • Name: endo-BCN-O-PNB
  • Chemical Name: endo-BCN-O-PNB
  • CAS Number: 1263166-91-1
  • Molecular Formula: C17H17NO5
  • Molecular Weight: 315.32
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 10:39:05
  • Modify Date: 2024-01-11 19:45:27
  • endo-BCN-O-PNB is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name endo-BCN-O-PNB
Synonyms MFCD19705415
Description endo-BCN-O-PNB is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula C17H17NO5
Molecular Weight 315.32