endo-BCN-O-PNB

Modify Date: 2024-01-11 19:45:27

endo-BCN-O-PNB Structure
endo-BCN-O-PNB structure
Common Name endo-BCN-O-PNB
CAS Number 1263166-91-1 Molecular Weight 315.32
Density N/A Boiling Point N/A
Molecular Formula C17H17NO5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of endo-BCN-O-PNB


endo-BCN-O-PNB is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name endo-BCN-O-PNB
Synonym More Synonyms

 endo-BCN-O-PNB Biological Activity

Description endo-BCN-O-PNB is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C17H17NO5
Molecular Weight 315.32

 Synonyms

MFCD19705415