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1835759-67-5

1835759-67-5 structure
1835759-67-5 structure
  • Name: Acid-PEG3-PFP ester
  • Chemical Name: Acid-PEG3-PFP ester
  • CAS Number: 1835759-67-5
  • Molecular Formula: C16H17F5O7
  • Molecular Weight: 416.29
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 19:57:54
  • Modify Date: 2024-01-27 13:03:11
  • Acid-PEG3-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Acid-PEG3-PFP ester
Synonyms MFCD29052176
Description Acid-PEG3-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C16H17F5O7
Molecular Weight 416.29