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1314378-13-6

1314378-13-6 structure
1314378-13-6 structure
  • Name: Bis-PEG3-PFP ester
  • Chemical Name: Bis-PEG3-PFP ester
  • CAS Number: 1314378-13-6
  • Molecular Formula: C22H16F10O7
  • Molecular Weight: 582.342272
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-12 03:48:27
  • Modify Date: 2024-01-15 07:07:32
  • Bis-PEG3-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Bis-PEG3-PFP ester
Synonyms BIS-PEG3-PFP ESTER
Description Bis-PEG3-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula C22H16F10O7
Molecular Weight 582.342272