2353409-96-6

2353409-96-6 structure

2353409-96-6 structure

Name: TCO-PEG6-NHS ester
Chemical Name: TCO-PEG6-NHS ester
CAS Number: 2353409-96-6
Molecular Formula: C₂₈H₄₆N₂O₁₂
Molecular Weight: 602.67
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-04-24 06:39:26
Modify Date: 2024-01-10 10:22:14
TCO-PEG6-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name	TCO-PEG6-NHS ester

Description	TCO-PEG6-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References	[1]. Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238.

Molecular Formula	C₂₈H₄₆N₂O₁₂
Molecular Weight	602.67