1818294-32-4
1818294-32-4 structure
- Name: SPDP-PEG6-NHS ester
- Chemical Name: SPDP-PEG6-NHS ester
- CAS Number: 1818294-32-4
- Molecular Formula: C27H41N3O11S2
- Molecular Weight: 647.758
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-15 05:25:33
- Modify Date: 2024-01-16 22:32:14
-
SPDP-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | SPDP-PEG6-NHS ester |
|---|---|
| Synonyms |
MFCD24539467
N-{21-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-21-oxo-3,6,9,12,15,18-hexaoxahenicos-1-yl}-3-(2-pyridinyldisulfanyl)propanamide Propanamide, N-[21-[(2,5-dioxo-1-pyrrolidinyl)oxy]-21-oxo-3,6,9,12,15,18-hexaoxaheneicos-1-yl]-3-(2-pyridinyldithio)- |
| Description | SPDP-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Molecular Formula | C27H41N3O11S2 |
| Molecular Weight | 647.758 |
| Exact Mass | 647.218262 |
| LogP | -1.60 |
| Index of Refraction | 1.565 |