1334177-88-6

1334177-88-6 structure
1334177-88-6 structure
  • Name: Cbz-NH-PEG12-C2-acid
  • Chemical Name: amino-dPEG 16-acid
  • CAS Number: 1334177-88-6
  • Molecular Formula: C35H61NO16
  • Molecular Weight: 751.85594
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-05 19:00:33
  • Modify Date: 2024-02-01 07:13:26
  • Cbz-NH-PEG12-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name amino-dPEG 16-acid
Synonyms CBZ-NH-PEG12-CH2CH2COOH
Description Cbz-NH-PEG12-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula C35H61NO16
Molecular Weight 751.85594