Cbz-NH-PEG12-C2-acid

Modify Date: 2024-02-01 07:13:26

Cbz-NH-PEG12-C2-acid structure	Common Name	Cbz-NH-PEG12-C2-acid
	CAS Number	1334177-88-6	Molecular Weight	751.85594
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₅H₆₁NO₁₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Cbz-NH-PEG12-C2-acid

Cbz-NH-PEG12-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	amino-dPEG 16-acid
Synonym	More Synonyms

Description	Cbz-NH-PEG12-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₃₅H₆₁NO₁₆
Molecular Weight	751.85594

CBZ-NH-PEG12-CH2CH2COOH