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67319-28-2

67319-28-2 structure
67319-28-2 structure
  • Name: m-PEG3-CH2CH2COOH
  • Chemical Name: 2,5,8,11-Tetraoxatetradecan-14-oic acid
  • CAS Number: 67319-28-2
  • Molecular Formula: C10H20O6
  • Molecular Weight: 236.262
  • Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
  • Create Date: 2018-06-05 14:45:32
  • Modify Date: 2024-01-05 11:59:51
  • m-PEG3-CH2CH2COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Name 2,5,8,11-Tetraoxatetradecan-14-oic acid
Synonyms 2,5,8,11-Tetraoxatetradecan-14-oic acid
MFCD11041124
Description m-PEG3-CH2CH2COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Related Catalog
Target

Non-cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Robert Lyon, et al. Pegylated drug-linkers for improved ligand-drug conjugate pharmacokinetics. WO2015057699A2.

Density 1.1±0.1 g/cm3
Boiling Point 352.3±32.0 °C at 760 mmHg
Molecular Formula C10H20O6
Molecular Weight 236.262
Flash Point 129.8±18.6 °C
Exact Mass 236.125992
LogP -1.35
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.445