62921-74-8

62921-74-8 structure

Name: m-PEG3-Tos
Chemical Name: 2-[2-(2-methoxyethoxy)ethoxy]ethanol,4-methylbenzenesulfonic acid
CAS Number: 62921-74-8
Molecular Formula: C₁₄H₂₂O₆S
Molecular Weight: 336.401
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2016-07-16 20:00:27
Modify Date: 2024-01-18 10:25:45
m-PEG3-Tos is a PEG-based PROTAC linker can be used in the synthesis of Silymarin (HY-W043277)[1].

Name	2-[2-(2-methoxyethoxy)ethoxy]ethanol,4-methylbenzenesulfonic acid
Synonyms	3,6,9-trioxadecyl tosylate 2-[2-(2-Methoxyethoxy)ethoxy]ethanol - 4-methylbenzenesulfonic acid (1:1) CH3(OCH2CH2)3OTs Ethanol, 2-[2-(2-methoxyethoxy)ethoxy]-, compd. with 4-methylbenzenesulfonic acid (1:1) Ethanol,2-[2-(2-methoxyethoxy)ethoxy]-,4-methylbenzenesulfonate CH3OC2H4OC2H4OC2H4OTs 2-[2-(2-Methoxyethoxy)ethoxy]ethyl 4-methylbenzenesulfonate triethyleneglycol monotosylate triethylene glycol methyl tosyl ether triethyleneglycol monomethyl ether tosylate

Description	m-PEG3-Tos is a PEG-based PROTAC linker can be used in the synthesis of Silymarin (HY-W043277)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References	[1]. Yuxia Zhao, et al. Derivative of silybin ethers, and synthetic method and application thereof. Patent CN105037337A.