GL Biochem (Shanghai) Ltd.
China
Product Name: 1-Methyl-L-tryptophan
Price: ￥Inquiry/1kg ￥Inquiry/100g
Purity: 99.0%
Stocking Period: Inquiry
Contact: Jackie Yang

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: (S)-Indoximod
Price: ￥198.0/20mg
Purity: 98.0%
Stocking Period: 2 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: 1-Methyl-L-tryptophan
Price: $280.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Nanjing Peptide Biotech Ltd
China
Product Name: 1-Methyl-L-tryptophan
Price: ￥Inquiry/10g ￥Inquiry/100g ￥Inquiry/1kg ￥Inquiry/10kg
Purity: 98.0%
Stocking Period: 7 Day
Contact: jom

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1-Methyl-L-tryptophan
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

21339-55-9

21339-55-9 structure

21339-55-9 structure

Name: (S)-Indoximod
Chemical Name: (2S)-2-amino-3-(1-methylindol-3-yl)propanoic acid
CAS Number: 21339-55-9
Molecular Formula: C₁₂H₁₄N₂O₂
Molecular Weight: 218.252
Catalog: Biochemical Chinese herbal medicine ingredients
Create Date: 2018-02-10 08:00:00
Modify Date: 2024-01-02 19:24:38
(S)-Indoximod (1-Methyl-L-tryptophan) is an inhibitor of indoleamine 2,3-dioxygenase (IDO). (S)-Indoximod can be used for the research of cancer[1][2].

Name	(2S)-2-amino-3-(1-methylindol-3-yl)propanoic acid
Synonyms	1-Methyl-L-tryptophan DL-1-Methyltryptophan MFCD00467133 L-Tryptophan, 1-methyl- 1-methyl-(D,L)-tryptophan 1-Methyl-L-tryptophane H-L-Trp(N-CH3)-OH H-Trp(1-Me)-OH BIDD:GT0440 (S)-2-Amino-3-(1-methyl-1H-indol-3-yl)propanoic acid

Description	(S)-Indoximod (1-Methyl-L-tryptophan) is an inhibitor of indoleamine 2,3-dioxygenase (IDO). (S)-Indoximod can be used for the research of cancer[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Indoleamine 2,3-Dioxygenase (IDO)
Target	Indoleamine 2,3-Dioxygenase (IDO)[1]
References	[1]. Huang GL, et, al. PEG-Poly(1-Methyl-l-Tryptophan)-Based Polymeric Micelles as Enzymatically Activated Inhibitors of Indoleamine 2,3-Dioxygenase. Nanomaterials (Basel). 2019 May 9;9(5):719. [2]. Liu X, et, al. 1-L-MT, an IDO inhibitor, prevented colitis-associated cancer by inducing CDC20 inhibition-mediated mitotic death of colon cancer cells. Int J Cancer. 2018 Sep 15;143(6):1516-1529.

Density	1.28
Boiling Point	429.3±35.0 °C at 760 mmHg
Melting Point	223-226 ºC
Molecular Formula	C₁₂H₁₄N₂O₂
Molecular Weight	218.252
Flash Point	213.4±25.9 °C
Exact Mass	218.105530
PSA	68.25000
LogP	1.43
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.625
Storage condition	2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YN7135000

CHEMICAL NAME :: L-Tryptophan, 1-methyl-

CAS REGISTRY NUMBER :: 21339-55-9

LAST UPDATED :: 198910

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C12-H14-N2-O2

MOLECULAR WEIGHT :: 218.28

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 286 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- Volume(issue)/page/year: 1,515,1976

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xn
Risk Phrases	R20/21/22
Safety Phrases	36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	YN7135000
HS Code	2933990090

73-22-3 structure

73-22-3

74-88-4 structure

74-88-4

~92%

21339-55-9 structure

21339-55-9

Literature: He, Bin; Song, Hao; Du, Yu; Qin, Yong Journal of Organic Chemistry, 2009 , vol. 74, # 1 p. 298 - 304

73-22-3 structure

73-22-3

~%

21339-55-9 structure

21339-55-9

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 17 p. 2471 - 2474

Precursor 2
73-22-3 74-88-4
DownStream 0

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%