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69-89-6

69-89-6 structure
69-89-6 structure

Name 7H-xanthine
Synonyms UREOUS ACID
Xan
xanthicoxide
Dioxopurine
9H-xanthine
2,5-DIFLUOROTHIOBENZAMIDE
usafcb-17
Xanthine
9H-Purine-2,6(1H,3H)-dione
Purine-2,6(1H,3H)-dione
Xanthin
ISOXANTHINE
2,6-Dihydroxypurine
MFCD00078453
3,7-dihydropurine-2,6-dione
Xanthione
EINECS 200-718-6
3,7-dihydro-1H-purine-2,6-dione
1H-Purine-2,6-dione, 3,7-dihydro-
3,7-dihydro-purine-2,6-dione
2,6(1H,3H)-Purinedione
Description Xanthine is a purine base found in most human body tissues and fluids and in other organisms.
Related Catalog
Target

Human Endogenous Metabolite

In Vitro A number of stimulants are derived from Xanthine including caffeine and theobromine. Xanthine is a product on the pathway of purine degradation. Xanthine is subsequently converted to uric acid by the action of the Xanthine oxidase enzyme.
Density 1.6±0.1 g/cm3
Boiling Point 834.9ºC at 760 mmHg
Melting Point 300 °C
Molecular Formula C5H4N4O2
Molecular Weight 152.111
Flash Point 458.7ºC
Exact Mass 152.033432
PSA 94.40000
LogP -0.81
Index of Refraction 1.636
Storage condition Store at RT.
Water Solubility NH4OH: freely soluble

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ZD7700000
CHEMICAL NAME :
Xanthine
CAS REGISTRY NUMBER :
69-89-6
LAST UPDATED :
199701
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C5-H4-N4-O2
MOLECULAR WEIGHT :
152.13
WISWESSER LINE NOTATION :
T56 BM DN FMVMVJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>3333 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3600 mg/kg/18W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Implant
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
80 mg/kg
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Kidney, Ureter, Bladder - tumors

MUTATION DATA

TYPE OF TEST :
Mutation in mammalian somatic cells
TEST SYSTEM :
Rodent - mouse Lymphocyte
DOSE/DURATION :
262 umol/L
REFERENCE :
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 3,193,1988 *** REVIEWS *** TOXICOLOGY REVIEW AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year: 23,6,1971 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3901 No. of Facilities: 68 (estimated) No. of Industries: 2 No. of Occupations: 5 No. of Employees: 2546 (estimated) No. of Female Employees: 786 (estimated)
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H317-H319
Precautionary Statements P280-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36;R43
Safety Phrases S36/37
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS ZD7700000
HS Code 2933990090
HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%