709-55-7

709-55-7 structure
709-55-7 structure
  • Name: Etilefrin
  • Chemical Name: 3-[2-(Ethylamino)-1-hydroxyethyl]phenol
  • CAS Number: 709-55-7
  • Molecular Formula: C10H15NO2
  • Molecular Weight: 181.23200
  • Catalog: Signaling Pathways Epigenetics AMPK
  • Create Date: 2018-02-11 08:00:00
  • Modify Date: 2024-01-19 17:44:05
  • Etilefrine (3-[2-(ethylamino)-1-hydroxyethyl]phenol) is an α adrenergic agonist[2]. Etilefrine also is an AMPK activator[1]. Etilefrine can be used for the research of postural hypotension[3].

Name 3-[2-(Ethylamino)-1-hydroxyethyl]phenol
Synonyms ethylphenylarsine chloride
Aethyl-chlor-phenyl-arsin
Arsine,chloroethylphenyl-(6CI,7CI,8CI)
Arsinous chloride,ethylphenyl
ethylphenylephrine
Aethyl-phenyl-dithiocarbamidsaeure,Ammonium-Salz
ethyl(phenyl)arsinous chloride
Aethylphenylarsinchlorid
Aethylphenylarsenchlorid
ethyl-chloro-phenyl-arsine
ammonium N-ethyl-N-phenyldithiocarbamate
Chloroethylphenylarsine
(RS)-etilefrine
2-ethylamino-1-(3-hydroxy-phenyl)-ethanol
ethyl-phenyl-dithiocarbamic acid,ammonium salt
Aethyl-phenyl-chlor-arsin
[3H]-(+/-)-Etilefrine
Ethylphenylchloroarsine
Description Etilefrine (3-[2-(ethylamino)-1-hydroxyethyl]phenol) is an α adrenergic agonist[2]. Etilefrine also is an AMPK activator[1]. Etilefrine can be used for the research of postural hypotension[3].
Related Catalog
Target

AMPK

In Vivo Etilefrine (0.1 mg/kg; i.v.) increases blood pressure (BP) and heart rate (HR), however, Etilefrine does not attenuate the decrease in BP induced by the tilt. Etilefrine also tends to increase cardiac output (CO)[3].
References

[1]. Sylvain Tollis, et al. Chemical Interrogation of Nuclear Size Identifies Compounds with Cancer Cell Line-Specific Effects on Migration and Invasion. ACS Chem Biol. 2022 Feb 24.

[2]. Chi Xu, et al. Accurate Drug Repositioning through Non-tissue-Specific Core Signatures from Cancer Transcriptomes. Cell Rep. 2018 Oct 9;25(2):523-535.e5.

[3]. R Yamazaki, et al. Effects of dihydroergotamine and Etilefrine on experimentally-induced postural hypotension in dogs. J Pharmacobiodyn. 1990 Sep;13(9):519-24.

Density 1.127 g/cm3
Boiling Point 351.7ºC at 760 mmHg
Molecular Formula C10H15NO2
Molecular Weight 181.23200
Flash Point 155.5ºC
Exact Mass 181.11000
PSA 52.49000
LogP 1.42600
Index of Refraction 1.561
HS Code 2922509090

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709-55-7 structure

709-55-7

Literature: Yakugaku Zasshi, , vol. 74, p. 318 Chem.Abstr., , p. 3960

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709-55-7 structure

709-55-7

Literature: Yakugaku Zasshi, , vol. 74, p. 318 Chem.Abstr., , p. 3960
HS Code 2922509090
Summary 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%