849773-63-3

849773-63-3 structure

Name: ARP 101
Chemical Name: Butanamide, 2-[([1,1'-biphenyl]-4-ylsulfonyl)(1-methylethoxy)amino]-N-hydroxy-3-methyl-, (2R)
CAS Number: 849773-63-3
Molecular Formula: C₂₀H₂₆N₂O₅S
Molecular Weight: 406.49600
Catalog: Signaling Pathways Metabolic Enzyme/Protease MMP
Create Date: 2017-10-04 05:25:46
Modify Date: 2024-01-12 17:10:55
ARP101 is a potent and selective inhibitor matrix metalloproteinase-2 (MMP-2). ARP101 induces autophagy-associated cell death in cancer cells. ARP101 is effective in inducing the formation of autophagosome and conversion of LC3I into LC3II[1].

Name	Butanamide, 2-[([1,1'-biphenyl]-4-ylsulfonyl)(1-methylethoxy)amino]-N-hydroxy-3-methyl-, (2R)
Synonyms	arp 101

Description	ARP101 is a potent and selective inhibitor matrix metalloproteinase-2 (MMP-2). ARP101 induces autophagy-associated cell death in cancer cells. ARP101 is effective in inducing the formation of autophagosome and conversion of LC3I into LC3II[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> MMP
References	[1]. Jo YK, et al. ARP101, a selective MMP-2 inhibitor, induces autophagy-associated cell death in cancer cells. Biochem Biophys Res Commun. 2011;404(4):1039-1043.