130955-39-4

130955-39-4 structure

Name: m-PEG6-Ms
Chemical Name: methanesulfonic acid,2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol
CAS Number: 130955-39-4
Molecular Formula: C₁₄H₃₀O₉S
Molecular Weight: 392.46300
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-06-18 18:12:54
Modify Date: 2024-01-09 18:07:54
m-PEG6-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	methanesulfonic acid,2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol
Synonyms	2,5,8,11,14,17-Hexaoxanonadecan-19-ol,methanesulfonate

Description	m-PEG6-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562