m-PEG6-Ms

Modify Date: 2024-01-09 18:07:54

m-PEG6-Ms Structure
m-PEG6-Ms structure
Common Name m-PEG6-Ms
CAS Number 130955-39-4 Molecular Weight 392.46300
Density N/A Boiling Point N/A
Molecular Formula C14H30O9S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG6-Ms


m-PEG6-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name methanesulfonic acid,2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol
Synonym More Synonyms

 m-PEG6-Ms Biological Activity

Description m-PEG6-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C14H30O9S
Molecular Weight 392.46300
Exact Mass 392.17200
PSA 138.36000
LogP 0.29290

 Synonyms

2,5,8,11,14,17-Hexaoxanonadecan-19-ol,methanesulfonate