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BTZ043 Racemate

Names

[ CAS No. ]:
957217-65-1

[ Name ]:
BTZ043 Racemate

[Synonym ]:
BTZ038
BTZ038,BTZ044
BTZ043 Racemate
BTZ043,BTZ038,BTZ044
BTZ043
BTZ044
2-{2-methyl-1,4-dioxa-8-azaspiro[4.5]decan-8-yl}-8-nitro-6-(trifluoromethyl)-1,3-benzothiazin-4-one

Biological Activity

[Description]:

BTZ043 Racemate is the racemate of BTZ043, BTZ043 is an inhibitor of decaprenyl-phosphoribose-epimerase (DprE1), and the antimicrobial activity of BTZ043 is more potent than BTZ043 Racemate.

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Bacterial
Research Areas >> Infection

[Target]

DprE1[1].


[References]

[1]. Gao C, et al. Synthesis and structure-activity relationships evaluation of benzothiazinone derivatives as potential anti-tubercular agents. Bioorg Med Chem Lett. 2013 Sep 1;23(17):4919-22.


[Related Small Molecules]

Puromycin 2HCl | Geneticin | Tunicamycin | Hygromycin B | Salinomycin | Avibactam sodium | Neomycin sulfate | Vaborbactam | Methicillin SodiuM | Rifampicin | Metronidazole | Carbenicillin disodium | Ceftazidime | Eravacycline dihydrochloride | cefotaxime sodium

Chemical & Physical Properties

[ Molecular Formula ]:
C17H16F3N3O5S

[ Molecular Weight ]:
431.38600

[ Exact Mass ]:
431.07600

[ PSA ]:
125.72000

[ LogP ]:
3.90350

[ Storage condition ]:
-20℃

Related Compounds