m-PEG8-Amine

Names

[ CAS No. ]:
869718-81-0

[ Name ]:
m-PEG8-Amine

[Synonym ]:
3,6,9,12,15,18,21,24-OCTAOXAPENTACOSAN-1-AMINE
AmbotzPEG1700

Biological Activity

[Description]:

m-PEG8-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Joshua D. Thoma, et al. Pyrrolobenzodiazepine antibody conjugates. WO2019126691A1.

Chemical & Physical Properties

[ Density]:
1.054

[ Boiling Point ]:
448ºC at 760 mmHg

[ Molecular Formula ]:
C₁₇H₃₇NO₈

[ Molecular Weight ]:
383.47800

[ Flash Point ]:
213.9ºC

[ Exact Mass ]:
383.25200

[ PSA ]:
99.86000

[ LogP ]:
0.40800

[ Storage condition ]:
-20 °C

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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