Ganoderic acid TR

Names

[ Name ]:
Ganoderic acid TR

[Synonym ]:
Lanosta-7,9(11),24-trien-26-oic acid, 15-hydroxy-3-oxo-, (15α,24E)-
(15α,24E)-15-Hydroxy-3-oxolanosta-7,9(11),24-trien-26-oic acid

Biological Activity

[Description]:

Ganoderic acid TR is a broad-spectrum inhibitor against influenza neuraminidases (NAs), particularly H5N1 and H1N1 neuraminidases. The IC50 values of 10.9 and 4.6 μM, respectively[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Influenza Virus

Research Areas >> Infection

[Target]

IC50: 10.9 (H5N1), 4.6 μM (H1N1)[1]

[References]

[1]. Zhu Q, et al. Inhibition of neuraminidase by Ganoderma triterpenoids and implications for neuraminidase inhibitor design. Sci Rep. 2015 Aug 26;5:13194.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
618.6±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₀H₄₄O₄

[ Molecular Weight ]:
468.668

[ Flash Point ]:
341.9±28.0 °C

[ Exact Mass ]:
468.323975

[ LogP ]:
6.72

[ Vapour Pressure ]:
0.0±4.1 mmHg at 25°C

[ Index of Refraction ]:
1.563

Related Compounds

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