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862893-75-2

862893-75-2 structure
862893-75-2 structure
  • Name: Ganoderic acid TR
  • Chemical Name: Ganoderic acid TR
  • CAS Number: 862893-75-2
  • Molecular Formula: C30H44O4
  • Molecular Weight: 468.668
  • Catalog: Signaling Pathways Anti-infection Influenza Virus
  • Create Date: 2018-10-16 13:30:37
  • Modify Date: 2024-01-10 11:37:22
  • Ganoderic acid TR is a broad-spectrum inhibitor against influenza neuraminidases (NAs), particularly H5N1 and H1N1 neuraminidases. The IC50 values of 10.9 and 4.6 μM, respectively[1].

Name Ganoderic acid TR
Synonyms Lanosta-7,9(11),24-trien-26-oic acid, 15-hydroxy-3-oxo-, (15α,24E)-
(15α,24E)-15-Hydroxy-3-oxolanosta-7,9(11),24-trien-26-oic acid
Description Ganoderic acid TR is a broad-spectrum inhibitor against influenza neuraminidases (NAs), particularly H5N1 and H1N1 neuraminidases. The IC50 values of 10.9 and 4.6 μM, respectively[1].
Related Catalog
Target

IC50: 10.9 (H5N1), 4.6 μM (H1N1)[1]

References

[1]. Zhu Q, et al. Inhibition of neuraminidase by Ganoderma triterpenoids and implications for neuraminidase inhibitor design. Sci Rep. 2015 Aug 26;5:13194.

Density 1.1±0.1 g/cm3
Boiling Point 618.6±55.0 °C at 760 mmHg
Molecular Formula C30H44O4
Molecular Weight 468.668
Flash Point 341.9±28.0 °C
Exact Mass 468.323975
LogP 6.72
Vapour Pressure 0.0±4.1 mmHg at 25°C
Index of Refraction 1.563