Lumefantrine
Names
[ CAS No. ]:
82186-77-4
[ Name ]:
Lumefantrine
[Synonym ]:
(±)-2-(Dibutylamino)-1-((9Z)-2,7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl)ethanol
(±)-2,7-Dichloro-9-((Z)-p-chlorobenzylidene)-α-((dibutylamino)methyl)fluorene-4-methanol
(Z)-2-(Dibutylamino)-1-(2,7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl)ethanol
Benflumetol
Lumefantrine
2-(Dibutylamino)-1-[(9Z)-2,7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl]ethanol
9H-Fluorene-4-methanol, 2,7-dichloro-9-[(4-chlorophenyl)methylene]-α-[(dibutylamino)methyl]-, (9Z)-
Biological Activity
[Description]:
[Related Catalog]:
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.252
[ Boiling Point ]:
642.5±55.0 °C at 760 mmHg
[ Melting Point ]:
129-131ºC
[ Molecular Formula ]:
C30H32Cl3NO
[ Molecular Weight ]:
528.940
[ Flash Point ]:
342.3±31.5 °C
[ Exact Mass ]:
527.154968
[ PSA ]:
23.47000
[ LogP ]:
11.37
[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C
[ Index of Refraction ]:
1.634
[ Storage condition ]:
Refrigerator
MSDS
Safety Information
[ RIDADR ]:
NONH for all modes of transport
[ HS Code ]:
2922199090
Customs
[ HS Code ]: 2922199090
[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
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Therapeutic blood plasma concentrations of anti-malarial drugs are essential for successful treatment. Pharmacokinetics of pharmaceutical compounds are dependent of adsorption, distribution, metabolis...
Comparison between Flow Cytometry, Microscopy, and Lactate Dehydrogenase-Based Enzyme-Linked Immunosorbent Assay for Plasmodium falciparum Drug Susceptibility Testing under Field Conditions.J. Clin. Microbiol. 53 , 3296-303, (2015)
Flow cytometry is an objective method for conducting in vitro antimalarial sensitivity assays with increasing potential for application in field sites. We examined in vitro susceptibility to seven ant...