Lumefantrine

Modify Date: 2024-01-01 18:21:47

Lumefantrine Structure
Lumefantrine structure
Common Name Lumefantrine
CAS Number 82186-77-4 Molecular Weight 528.940
Density 1.252 Boiling Point 642.5±55.0 °C at 760 mmHg
Molecular Formula C30H32Cl3NO Melting Point 129-131ºC
MSDS Chinese USA Flash Point 342.3±31.5 °C

 Use of Lumefantrine


Lumefantrine is an antimalarial drug, used in combination with Artemether. The artemether-lumefantrine (AL) as the first- and second-line anti-malarial drugs.

 Names

Name lumefantrine
Synonym More Synonyms

 Lumefantrine Biological Activity

Description Lumefantrine is an antimalarial drug, used in combination with Artemether. The artemether-lumefantrine (AL) as the first- and second-line anti-malarial drugs.
Related Catalog
References

[1]. Ndounga M, et al. Artesunate-amodiaquine versus artemether-lumefantrine for the treatment of acute uncomplicated malaria in Congolese children under 10 years old living in a suburban area: a randomized study. Malar J. 2015 Oct 29;14(1):423.

 Chemical & Physical Properties

Density 1.252
Boiling Point 642.5±55.0 °C at 760 mmHg
Melting Point 129-131ºC
Molecular Formula C30H32Cl3NO
Molecular Weight 528.940
Flash Point 342.3±31.5 °C
Exact Mass 527.154968
PSA 23.47000
LogP 11.37
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.634
Storage condition Refrigerator

 Safety Information

RIDADR NONH for all modes of transport
HS Code 2922199090

 Customs

HS Code 2922199090
Summary 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles56

More Articles
Antibody and T-cell responses associated with experimental human malaria infection or vaccination show limited relationships.

Immunology 145(1) , 71-81, (2015)

This study examined specific antibody and T-cell responses associated with experimental malaria infection or malaria vaccination, in malaria-naive human volunteers within phase I/IIa vaccine trials, w...

Atovaquone and quinine anti-malarials inhibit ATP binding cassette transporter activity.

Malaria Journal 13 , 359, (2014)

Therapeutic blood plasma concentrations of anti-malarial drugs are essential for successful treatment. Pharmacokinetics of pharmaceutical compounds are dependent of adsorption, distribution, metabolis...

Comparison between Flow Cytometry, Microscopy, and Lactate Dehydrogenase-Based Enzyme-Linked Immunosorbent Assay for Plasmodium falciparum Drug Susceptibility Testing under Field Conditions.

J. Clin. Microbiol. 53 , 3296-303, (2015)

Flow cytometry is an objective method for conducting in vitro antimalarial sensitivity assays with increasing potential for application in field sites. We examined in vitro susceptibility to seven ant...

 Synonyms

(±)-2-(Dibutylamino)-1-((9Z)-2,7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl)ethanol
(±)-2,7-Dichloro-9-((Z)-p-chlorobenzylidene)-α-((dibutylamino)methyl)fluorene-4-methanol
(Z)-2-(Dibutylamino)-1-(2,7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl)ethanol
Benflumetol
Lumefantrine
2-(Dibutylamino)-1-[(9Z)-2,7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl]ethanol
9H-Fluorene-4-methanol, 2,7-dichloro-9-[(4-chlorophenyl)methylene]-α-[(dibutylamino)methyl]-, (9Z)-
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  • Purity: 98.0%
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