AChE/BChE-IN-11

Names

[ CAS No. ]:
80443-12-5

[ Name ]:
AChE/BChE-IN-11

Biological Activity

[Description]:

AChE/BChE-IN-11 (compound 1) is a potent is a dual AChE and BChE inhibitor with IC50 values of 70 and 71 μM for AChE and BChE, respectively. AChE/BChE-IN-11 is a natural product that could be isolated from the leaf of artichoke . AChE/BChE-IN-11 can be used in research of Alzheimer’s disease (AD) research[1].

[Related Catalog]:

Research Areas >> Neurological Disease
Signaling Pathways >> Neuronal Signaling >> AChE

[Target]

AChE:70 μM (IC50)

BChE:71 μM (IC50)


[References]

[1]. Elsebai MF, et, al. X-ray crystalographic data, absolute configuration, and anticholinesterase effect of dihydromyricitrin 3-O-rhamnoside. Sci Rep. 2022 Nov 1;12(1):18351.  

Chemical & Physical Properties

[ Molecular Formula ]:
C21H22O12

[ Molecular Weight ]:
466.39200

[ Exact Mass ]:
466.11100

[ PSA ]:
206.60000

Related Compounds