AChE/BChE-IN-4

Names

[ CAS No. ]:
2294963-47-4

[ Name ]:
AChE/BChE-IN-4

Biological Activity

[Description]:

AChE/BChE-IN-4 (BMC-3) is a dual AChE and BChE inhibitor with IC50 values of 792 nM and 2.2 nM against human AChE (hAChE) and human BChE (hBChE), respectively. AChE/BChE-IN-4 can cross the BBB[1].

[Related Catalog]:

Research Areas >> Neurological Disease
Signaling Pathways >> Neuronal Signaling >> AChE

[Target]

IC50: 2.2 nM (hBChE), 792 nM (hAChE)[1]


[References]

[1]. Wu J, et al. Design, synthesis and biological evaluation of novel carbamates as potential inhibitors of acetylcholinesterase and butyrylcholinesterase. Bioorg Med Chem. 2020 Mar 1;28(5):115324.

Chemical & Physical Properties

[ Molecular Formula ]:
C17H26N2O3

[ Molecular Weight ]:
306.40

Related Compounds