Pirlimycin

Names

[ Name ]:
Pirlimycin

[Synonym ]:
Pirlimycin
UNII-LM19JT6G5K
Pirlimycinum
Pirlimycine
Pirlimycina

Biological Activity

[Description]:

Pirlimycin (RU 38882), a lincosamide antibiotic, is active against Gram-positive bacteria. Pirlimycin acts by inhibiting bacterial protein synthesis via binding with the 50S subunit of the ribosome[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Birkenmeyer RD, et, al. Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. J Med Chem. 1984 Feb;27(2):216-23.

Chemical & Physical Properties

[ Density]:
1.31g/cm3

[ Boiling Point ]:
643.9ºC at 760 mmHg

[ Molecular Formula ]:
C₁₇H₃₁ClN₂O₅S

[ Molecular Weight ]:
410.96

[ Flash Point ]:
343.2ºC

[ Exact Mass ]:
410.16400

[ PSA ]:
136.35000

[ LogP ]:
0.76700

[ Index of Refraction ]:
1.574

Synthetic Route

Click to get detail synthetic route

Related Compounds

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