79548-73-5

79548-73-5 structure

Name: Pirlimycin
Chemical Name: (2S,4R)-N-[(1S,2S)-2-chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-4-ethylpiperidine-2-carboxamide
CAS Number: 79548-73-5
Molecular Formula: C₁₇H₃₁ClN₂O₅S
Molecular Weight: 410.96
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-05-02 08:00:00
Modify Date: 2025-08-25 12:10:13
Pirlimycin (RU 38882), a lincosamide antibiotic, is active against Gram-positive bacteria. Pirlimycin acts by inhibiting bacterial protein synthesis via binding with the 50S subunit of the ribosome[1].

Name	(2S,4R)-N-[(1S,2S)-2-chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-4-ethylpiperidine-2-carboxamide
Synonyms	Pirlimycin UNII-LM19JT6G5K Pirlimycinum Pirlimycine Pirlimycina

Description	Pirlimycin (RU 38882), a lincosamide antibiotic, is active against Gram-positive bacteria. Pirlimycin acts by inhibiting bacterial protein synthesis via binding with the 50S subunit of the ribosome[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Birkenmeyer RD, et, al. Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. J Med Chem. 1984 Feb;27(2):216-23.

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79548-73-5

Literature: Journal of Medicinal Chemistry, , vol. 27, # 2 p. 216 - 223