Urea, (diphenylmethyl)- (8CI)(9CI)
Names
[ CAS No. ]:
724-18-5
[ Name ]:
Urea, (diphenylmethyl)- (8CI)(9CI)
[Synonym ]:
Urea,1-diphenylmethyl
Benzhydryl-harnstoff
Chemical & Physical Properties
[ Density]:
1.156g/cm3
[ Boiling Point ]:
389.7ºC at 760 mmHg
[ Molecular Formula ]:
C14H14N2O
[ Molecular Weight ]:
226.27400
[ Flash Point ]:
189.5ºC
[ Exact Mass ]:
226.11100
[ PSA ]:
55.12000
[ LogP ]:
3.53550
[ Index of Refraction ]:
1.604
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YT2000000
- CHEMICAL NAME :
- Urea, 1-diphenylmethyl-
- CAS REGISTRY NUMBER :
- 724-18-5
- BEILSTEIN REFERENCE NO. :
- 2807619
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C14-H14-N2-O
- MOLECULAR WEIGHT :
- 226.30
- WISWESSER LINE NOTATION :
- ZVM1R DR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >4 gm/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 39,355,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 39,355,1976 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 45500 mg/kg/13W-I
- TOXIC EFFECTS :
- Liver - hepatitis (hepatocellular necrosis), zonal Kidney, Ureter, Bladder - proteinuria Endocrine - hyperglycemia
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 39,355,1976
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Related Compounds
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