Dapsone D8

Names

[ Name ]:
Dapsone D8

[Synonym ]:
deuterated 4,4'-diaminodiphenylsulfone
4,4 inverted exclamation mark-Sulfonylbisbenzeneamine-D8
4,4'-Sulfonylbis-benzen-2,3,5,6-d4-amine

Biological Activity

[Description]:

Dapsone D8 is a deuterium labeled Dapsone. Dapsone is an anti-inflammatory and antibacterial compound that is widely used in the treatment of leprosy, malaria, acne, and various immune disorders. Dapsone is acetylated in the liver to monoacetyldapsone, the major metabolite, and other mono and diacetyl derivatives, and subsequently deacetylated back to diaminodiphenylsulfone (dapsone) until a state of equilibrium is achieved.

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Bacterial

Chemical & Physical Properties

[ Melting Point ]:
164-167°C

[ Molecular Formula ]:
C₁₂H₄D₈N₂O₂S

[ Molecular Weight ]:
248.30100

[ Exact Mass ]:
248.06200

[ PSA ]:
94.56000

[ LogP ]:
3.92700

[ Storage condition ]:
-20°C Freezer

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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