557794-38-4
557794-38-4 structure
- Name: Dapsone D8
- Chemical Name: 4-(4-amino-2,3,5,6-tetradeuteriophenyl)sulfonyl-2,3,5,6-tetradeuterioaniline
- CAS Number: 557794-38-4
- Molecular Formula: C12H4D8N2O2S
- Molecular Weight: 248.30100
- Catalog: Chemical reagent Deuterated reagent
- Create Date: 2016-01-17 21:45:32
- Modify Date: 2024-01-04 14:12:11
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Dapsone D8 is a deuterium labeled Dapsone. Dapsone is an anti-inflammatory and antibacterial compound that is widely used in the treatment of leprosy, malaria, acne, and various immune disorders. Dapsone is acetylated in the liver to monoacetyldapsone, the major metabolite, and other mono and diacetyl derivatives, and subsequently deacetylated back to diaminodiphenylsulfone (dapsone) until a state of equilibrium is achieved.
| Name | 4-(4-amino-2,3,5,6-tetradeuteriophenyl)sulfonyl-2,3,5,6-tetradeuterioaniline |
|---|---|
| Synonyms |
deuterated 4,4'-diaminodiphenylsulfone
4,4 inverted exclamation mark-Sulfonylbisbenzeneamine-D8 4,4'-Sulfonylbis-benzen-2,3,5,6-d4-amine |
| Description | Dapsone D8 is a deuterium labeled Dapsone. Dapsone is an anti-inflammatory and antibacterial compound that is widely used in the treatment of leprosy, malaria, acne, and various immune disorders. Dapsone is acetylated in the liver to monoacetyldapsone, the major metabolite, and other mono and diacetyl derivatives, and subsequently deacetylated back to diaminodiphenylsulfone (dapsone) until a state of equilibrium is achieved. |
|---|---|
| Related Catalog |
| Melting Point | 164-167°C |
|---|---|
| Molecular Formula | C12H4D8N2O2S |
| Molecular Weight | 248.30100 |
| Exact Mass | 248.06200 |
| PSA | 94.56000 |
| LogP | 3.92700 |
| Storage condition | -20°C Freezer |
|
~94%
557794-38-4 |
| Literature: WAKO PURE CHEMICAL INDUSTRIES, LTD. Patent: US2008/45724 A1, 2008 ; Location in patent: Page/Page column 18 ; |
|
~%
557794-38-4 |
| Literature: Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 46, # 2 p. 107 - 114 |
|
~%
557794-38-4 |
| Literature: Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 46, # 2 p. 107 - 114 |
|
~%
557794-38-4 |
| Literature: Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 46, # 2 p. 107 - 114 |
|
~80%
557794-38-4 |
| Literature: Gannett, Peter M.; Johnson II, Edward M.; Grimes, Michael A.; Myers, Alan L.; Deavers III, Robert E.; Tracy, Timothy S. Journal of Labelled Compounds and Radiopharmaceuticals, 2003 , vol. 46, # 2 p. 107 - 114 |
| Precursor 5 | |
|---|---|
| DownStream 0 | |