3-BROMO-1,2-PROPANEDIOL

Names

[ CAS No. ]:
4704-77-2

[ Name ]:
3-BROMO-1,2-PROPANEDIOL

[Synonym ]:
EINECS 225-186-2
3-BROMO-1,2-PROPANEDIOL
MFCD00004711

Chemical & Physical Properties

[ Density]:
1.789g/cm3

[ Boiling Point ]:
254ºC at 760mmHg

[ Molecular Formula ]:
C₃H₇BrO₂

[ Molecular Weight ]:
154.99000

[ Flash Point ]:
126.5ºC

[ Exact Mass ]:
153.96300

[ PSA ]:
40.46000

[ Appearance of Characters ]:
Viscous Liquid | Clear colorless to yellow

[ Index of Refraction ]:
n20/D 1.518(lit.)

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TY3360000

CHEMICAL NAME :: 1,2-Propanediol, 3-bromo-

CAS REGISTRY NUMBER :: 4704-77-2

BEILSTEIN REFERENCE NO. :: 1719124

LAST UPDATED :: 199712

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C3-H7-Br-O2

MOLECULAR WEIGHT :: 155.01

WISWESSER LINE NOTATION :: Q1YQ1E

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 212 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 5 umol/plate

REFERENCE :: JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- Volume(issue)/page/year: 5,1149,1979

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C

[ Risk Phrases ]:
34

[ Safety Phrases ]:
S26;S45;S36/S37/S39

[ RIDADR ]:
UN 1760 8/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
TY3360000

[ Packaging Group ]:
III

[ Hazard Class ]:
8

Precursor & DownStream

Precursor

DownStream

Articles

Glycerol 3-phosphate dehydrogenase of boar spermatozoa: inhibition by alpha-bromohydrin phosphate.

J. Reprod. Fertil. 108(1) , 95-100, (1996)

Boar spermatozoa incubated with glycerol 3-phosphate as substrate produced CO2 and an accumulation of dihydroxyacetone phosphate and fructose-1,6-bisphosphate. The rate of oxidation of glycerol 3-phos...

Renal and spermatozoal toxicity of alpha-bromohydrin, 3-bromolactate and 3-bromopyruvate.

J. Appl. Toxicol. 16(1) , 57-63, (1996)

(R,S)- and (R)-3-Bromopropan-1,2-diol (alpha-bromohydrin) produced diuresis and glucosuria when administered to male rats but had no effect on the metabolic activity of rat kidney tubules in vitro. Th...